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Publicatie in Patient Education and Counseling

In december 2018 is een nieuwe publicatie verschenen met data uit de NABON Breast Cancer Audit (NBCA). Het artikel is uitgebracht in Patient Education and Counseling:

Current decisions on neoadjuvant chemotherapy for early breast cancer: Experts' experiences in the Netherlands.

Auteurs: Spronk, P. E. R., de Ligt, K. M., van Bommel, A. C. M., Siesling, S., Smorenburg, C. H., & Peeters, M. V.

Lees hier het volledige artikel. De samenvatting van de publicatie kunt u hieronder vinden:


To evaluate the opinion of surgical and medical oncologists on neoadjuvant chemotherapy (NAC) for early breast cancer.


Surgical and medical oncologists (N = 292) participating in breast cancer care in the Netherlands were invited for a 20-question survey on the influence of patient, disease, and management related factors on their decisions towards NAC.


A total of 138 surgical and medical oncologists from 64 out of 89 different Dutch hospitals completed the survey. NAC was recommended for locally advanced breast cancer (94%) and for downstaging to enable breast conserving surgery (BCS) (75%). Despite willingness to downstage, 64% of clinicians routinely recommended NAC when systemic therapy was indicated preoperatively. Reported reasons to refrain from NAC are comorbidities (68%), age >70 years (52%), and WHO-performance status ≥2 (93%). Opinions on NAC and surgical management were inconclusive; while 75% recommends NAC to enable BCS, some stated that BCS after NAC increases the risk of a non-radical resection (21%), surgical complications (9%) and recurrence of disease (5%).


This article emphasizes the need for more consensus among specialists on the indications for NAC in early BC patients. Unambiguous and evidence-based treatment information could improve doctor-patient communication, supporting the patient in chemotherapy timing decision-making.